Noncommunicable diseases are a significant public health problem in Thailand and worldwide. In Thailand, Hypertension is found among people as much as 24.7% of, predominantly in people older than 80; 64.9% are found to have hypertension. Hypertension is also associated with Macrovascular complications. We determined the prevalence and risk factors of Macrovascular complications, which consisted of Coronary heart disease and cerebrovascular disease among hypertensive patients in Patthana Nikhom hospital, Lopburi province, Thailand. A Cross-sectional study was performed on Adults with hypertension who visited Patthana Nikhom hospital between 2017-2019. The secondary data were retrieved from the electronic medical records of Patthana Nikhom hospital. Coronary heart disease was defined by ICD-10, including I20-I21, and Cerebrovascular disease was defined by ICD-10, including I60-I63. Descriptive statistics were used to analyze demographic data and incidence. Logistic regression analysis was performed to determine the odds ratio for macrovascular complication. A total of 9,025 patients with hypertension were enrolled in the study. We analyzed only myocardial infarction and cerebrovascular disease due to the low prevalence of peripheral arterial disease recorded in Patthana Nikhom hospital. In myocardial infarction, after adjusting for the potential confounding factor, we found that the risk of myocardial infarction was higher in age group (95%CI 1.038-1.055, p-value = <0.001), male vs. female (95%CI 1.107-1.659, p-value =0.003), dyslipidemia (95%CI 1.013-1.794, p-value =0.041) and gouty arthritis (95%CI 1.088-2.456, p-value =0.018).
Contrary to the results shown above, after adjusting for the potential confounding factor, we found that the protective factor of myocardial infraction was alcohol drinking (95%CI 0.285-0.865, p-value =0.013). In cerebrovascular disease, after adjusting for the potential confounding factor, we found that the risk of cerebrovascular disease was higher in age group (95%CI 1.021-1.034, p-value =<0.001), male vs. female (95%CI 1.778-2.52, p-value =<0.001), T2DM (95%CI 1.054-1.483, p-value =0.01) and higher diastolic blood pressure (95%CI 1.001-1.008, p-value =0.014).
